What happens to the metabolic rate of brown adipose tissue when norepinephrine binds to its receptors?

💡 Explanation

The metabolic rate increases because norepinephrine binding stimulates UCP1, an uncoupling protein, in brown adipose tissue mitochondria. This process allows protons to leak across the inner mitochondrial membrane, generating heat rather than ATP; therefore, heat production increases, rather than decreasing or remaining constant due to other regulatory mechanisms.

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