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← ScienceWhich consequence diminishes the stability of the alpha helix structure?
A)Proline disrupts backbone hydrogen bonding✓
B)Hydrophobic forces promote tight coiling
C)Van der Waals repulsion stabilizes structure
D)Charged side-chains enhance ionic interactions
💡 Explanation
Alpha helix stability diminishes if proline is present because its rigid cyclic structure prevents amide hydrogen atoms participating in *hydrogen bonding*, therefore destabilizing the helix, rather than stabilizing it via hydrophobic interactions.
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