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Human Body & Health

Which consequence results when damage reduces gastric parietal cell mass?

A)Decreased intrinsic factor causes pernicious anemia
B)Reduced bicarbonate buffers duodenal acidity
C)Lowered pepsin production inhibits proteinolysis
D)Impaired mucus secretion damages epithelium

💡 Explanation

Reduced parietal cell mass impairs hydrochloric acid secretion; this decreases intrinsic factor production; therefore less vitamin B12 absorption causes pernicious anemia, rather than affected bicarbonates or pepsin because acid output governs intrinsic factor availability.

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