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Human Body & Health

Which consequence results when melanocyte-stimulating hormone (MSH) overstimulates receptors?

A)Hypoglycemia via peripheral glucose uptake
B)Hyperpigmentation via melanin production
C)Increased erythropoiesis via kidney signaling
D)Thyroid dysfunction via TSH suppression

💡 Explanation

MSH overstimulation triggers melanocytes' activation in the skin, via the melanocortin 1 receptor (MC1R), leading to melanin synthesis and subsequent hyperpigmentation; therefore, darkening of the skin occurs, rather than metabolic changes or thyroid issues, because differing hormonal and cellular pathways control those mechanisms.

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