Which developmental constraint arises when damage occurs to imaginal disc cells in fly larvae?

💡 Explanation

When imaginal disc cells sustain irreparable damage, apoptosis occurs and compensatory proliferation might only partially restore the cell population because disc size is tightly regulated by hormones, limiting the extent of regeneration, leaving adults with reduced or deformed appendages. Therefore regenerative capacity declines, rather than germline mutation, aging, or suppressed immunity which involve unrelated mechanisms.

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