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Which effect dominates dissociation energy changes when hydrogen bonds length variations in DNA arise?

A)Dipole-dipole interaction alteration effects
B)Entropy increase caused by base pair flipping
C)Electrostatic potential energy changes
D)Covalent bond breaking in phosphodiester bonds

💡 Explanation

Decreasing length in hydrogen bonds alter hydrogen bonding strength because electrostatic potential energy between the donor and acceptor atoms becomes more negative as shorter distance strengthens attraction between partially charged hydrogen and acceptor atoms. Therefore electrostatic potential energy changes dominate dissociation energy rather than dipole-dipole, entropy, or covalent bonds.

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