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Human Body & Health

Which effect results when regulatory T cell (Treg) function declines during chronic hepatitis B infection?

A)Increased liver cell regeneration
B)Enhanced viral clearance efficiency
C)Persistent liver inflammation and damage
D)Suppressed antibody production response

💡 Explanation

Persistent liver inflammation and damage occur because declining Treg function impairs immune tolerance to viral antigens. This failure leads to unchecked cytotoxic T cell activity, therefore the liver sustains continuous immune-mediated injury, rather than undergoing resolution with controlled inflammation.

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