Which failure mode becomes likely in asthma patients who overuse beta-agonist inhalers alongside environmental histamine exposure?

💡 Explanation

Overuse of beta-agonist inhalers can lead to beta-receptor desensitization; environmental histamine increases bronchoconstriction. Because the beta-agonist becomes less effective, the bronchodilator response diminishes, therefore airway constriction increases, rather than alternatives like mucus plug formation, which primarily stem from inflammatory processes.

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