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Human Body & Health

Which hormonal outcome occurs when disrupted sleep chronically elevates cortisol?

A)Impaired negative feedback regulation of ACTH
B)Increased thyroid stimulating hormone production
C)Reduced somatic growth hormone secretion
D)Enhanced glucagon response to hypoglycemia

💡 Explanation

Disrupted sleep raises cortisol chronically, disturbing normal diurnal patterns, because the hypothalamic-pituitary-adrenal (HPA) axis drives hypercortisolism. An increased cortisol concentration desensitizes receptors, therefore feedback inhibition is stunted, rather than normal regulation of the ACTH hormone output.

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