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Human Body & Health

Why does an elderly patient undergoing hip replacement with pre-existing sarcopenia often experience impaired post-operative muscle recovery?

A)Increased bone marrow cellularity inhibits healing
B)Decreased systemic inflammation reduces muscle stimuli
C)Reduced nerve growth factor enhances reinnervation
D)Impaired satellite cell activation limits regeneration

💡 Explanation

Sarcopenia decreases the number and function of muscle satellite cells, which are crucial for muscle fiber repair and regeneration after injury, because this limits the myogenic response. Therefore, muscle recovery is impaired, rather than improved, through other inflammatory or neural mechanisms.

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