What distinguishes the immune response to a vaccine with an adjuvant compared to a vaccine without an adjuvant?

💡 Explanation

Adjuvants enhance the immune response, specifically promoting affinity maturation of B cells. This occurs because adjuvants activate antigen-presenting cells, leading to stronger B cell activation and selection for higher-affinity antibodies; therefore, affinity maturation is enhanced rather than reduced as with vaccines without adjuvants.

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