Which outcome is most likely during alcohol withdrawal, specifically regarding the GABAergic system's response?

💡 Explanation

During chronic alcohol exposure, the brain adapts by downregulating GABA receptors to maintain homeostasis. Withdrawal leads to reduced GABA receptor responsiveness because the sudden absence of alcohol's enhancing effects leaves the inhibitory system underactive; therefore, the central nervous system becomes hyperexcitable, rather than more sensitive.

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