Which outcome occurs when a lysine residue is exposed to formaldehyde during histology sample preparation?

💡 Explanation

Protein cross-linking increases because formaldehyde facilitates methylene bridge formation via methylene bridge formation by reacting with amine groups on lysine. This causes covalent bonds, therefore cross-linking becomes dominant, rather than hydrophobic interactions or reduced glycosylation, which do not involve formaldehyde's interactions with amine groups.

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