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Human Body & Health

Which outcome occurs when complement C5a over-activates endothelial cells?

A)Capillary permeability temporarily increases
B)Infected cells undergo apoptosis directly
C)T-cell-mediated immunity temporarily blocked
D)B-cell class switching permanently impaired

💡 Explanation

Increased capillary dilation follows because complement anaphylatoxins like C5a trigger increased vascular permeability. Therefore capillaries temporarily become leaky, rather than targetting infected apoptotic cells, because T or B cells have different functional mechanisms.

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