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← Human Body & HealthA cancer cell with a mutated growth factor receptor bypasses the G1 checkpoint; which outcome is most likely if pro-apoptotic signals are ineffective?
A)Increased DNA repair efficiency
B)Uncontrolled cell proliferation✓
C)Enhanced cellular differentiation
D)Reduced metabolic activity
💡 Explanation
If pro-apoptotic signals are ineffective, the cell cannot undergo programmed cell death. Because apoptosis is the mechanism preventing cells with DNA damage from replicating, the mutated cell will proliferate uncontrollably, rather than being eliminated or repaired.
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