Which outcome occurs when high concentrations of product inhibit an enzyme-catalyzed reaction in a closed system?

💡 Explanation

When high product concentrations exist, product inhibition slows or reverses the reaction towards reactants because the equilibrium shifts to relieve the product excess (Le Chatelier's principle). Therefore equilibrium shifts towards reactant formation, rather than faster rates, denaturation, or substrate affinity changes which involve alternative mechanisms.

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