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Human Body & Health

Which outcome reduces inflammation when apoptotic cells accumulate?

A)Impaired efferocytosis leading to secondary necrosis
B)Uncontrolled degranulation amplifies local damage
C)Excess lymphocyte production intensifies response
D)Increased macrophage recruitment reduces healing

💡 Explanation

Secondary necrosis increases when clearance is insufficient; therefore impaired efferocytosis from failed *phagocytosis* increases inflammatory signals because dead cells rupture rather than undergo ordered removal, resulting in more inflammation relative to proper phagocytic clearance.

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