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Human Body & Health

Which risk increases as parathyroid hormone (PTH) rises excessively despite sufficient vitamin D and calcium intake, especially when kidney function declines?

A)Increased bone mineral density overall
B)Reduced phosphate absorption in gut
C)Elevated calcitonin release thyroid
D)Increased bone mineral resorption rate

💡 Explanation

Increased PTH stimulates osteoclast activity to release calcium from bone, and this resorption dominates when kidneys cannot efficiently process mineral balance; therefore, bone mineral density decreases, rather than increases, because excessive bone breakdown outpaces formation.

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