Which risk increases as allergen-specific IgE production rises during the sensitization phase leading up to anaphylaxis?

💡 Explanation

Anaphylaxis risk increases with IgE because increased IgE binds to mast cells and basophils. Subsequent allergen exposure causes cross-linking of IgE receptors, triggering excessive mast cell degranulation and release of histamine and other mediators, therefore leading to systemic vasodilation and bronchoconstriction, rather than the other immune processes.

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