Why does a prolonged state of malnutrition hinder skin's ability to resist bacterial infection despite adequate sebum production?

💡 Explanation

Malnutrition reduces amino acid availability, which impairs collagen synthesis, a key component of skin barrier function. The impaired integrity allows bacterial penetration, because the structural barrier is weakened. Therefore, the skin is more susceptible to infection rather than histamine, lymphatic, or cortisol-mediated immune responses.

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