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Human Body & Health

Why does an ACL tear, disrupting knee joint biomechanics, often result in osteoarthritis years later?

A)Reduced synovial fluid volume
B)Increased chondrocyte proliferation rates
C)Enhanced meniscal cartilage regeneration
D)Altered joint loading and instability

💡 Explanation

Altered joint loading after an ACL tear leads to abnormal stress distribution within the knee because the mechanotransduction process is disrupted, and therefore the cartilage degrades unevenly, causing osteoarthritis rather than maintaining normal cartilage homeostasis via balanced loading patterns.

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