Why does bariatric surgery often lead to remission of type 2 diabetes, especially considering the altered gut hormone signaling?

💡 Explanation

Bariatric surgery improves type 2 diabetes through hormonal changes, because it enhances GLP-1 secretion. GLP-1 increases insulin secretion and sensitivity, therefore reversing hyperglycemia and insulin resistance, rather than ghrelin raising blood sugar or leptin causing resistance.

• In an asthmatic patient experiencing acute bronchospasm after exposure to pollen, which mechanism explains why administering a beta-agonist inhaler might not fully resolve the respiratory distress?
• What distinguishes the urea cycle in the liver from the Cori cycle during prolonged starvation?
• An individual with significantly reduced sebum production experiences increased skin flaking and sensitivity; which mechanism best explains this outcome?
• Why does decreased muscle mass (sarcopenia) during aging exacerbate insulin resistance in skeletal muscle?
• Why does the brainstem trigger increased respiration when the ventilation-perfusion ratio decreases significantly in a lung region affected by localized pneumonia?
• Why does liver damage due to chronic alcohol consumption elevate blood ammonia levels?