Why does chronic primary hyperaldosteronism often result in sustained hypertension, even if arterial baroreceptors are functioning normally?

💡 Explanation

Chronic hyperaldosteronism leads to increased sodium reabsorption in the kidneys, which expands the plasma volume. Because this volume expansion causes increased blood pressure, therefore hypertension persists, rather than being regulated by baroreceptors alone, because volume overload overcomes normal baroreflex buffering.

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