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Human Body & Health

Why does compulsive drug use continue, despite negative consequences, in addiction?

A)Homeostatic set points restore balance
B)Dopamine hijacks the reward circuitry
C)Prefrontal cortex inhibits impulsivity
D)Serotonin modulates behavioral reinforcement

💡 Explanation

Addiction continues due to dopamine dysregulation; drugs cause a surge of dopamine in the nucleus accumbens, which reinforces drug-seeking behavior, hijacking the brain's reward circuitry, because the brain interprets drug use as highly rewarding. Therefore, compulsive use continues, rather than being inhibited by cognitive control.

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