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Human Body & Health

Why does follicular development cease prematurely when inhibin secretion from developing follicles decreases rapidly during the luteal-follicular transition?

A)Estrogen receptors become desensitized
B)FSH secretion undergoes unchecked escalation
C)LH surges remain continuously elevated
D)Progesterone maintains dominant inhibition

💡 Explanation

Reduced inhibin fails to suppress FSH secretion via negative feedback, because the pituitary continues to release FSH unchecked. Therefore, follicle development ceases due to a lack of coordinated hormonal signaling, rather than through estrogen receptor desensitization or sustained LH/progesterone influence.

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