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← Human Body & HealthWhy does proteinuria (protein in urine) often indicate kidney damage rather than transient dehydration?
A)Increased ADH reduces protein reabsorption
B)Muscle breakdown overwhelms filtration capacity
C)Glomerular filtration barrier becomes permeable✓
D)Tubular secretion actively excretes proteins
💡 Explanation
Proteinuria signals kidney damage because the glomerular filtration barrier, normally impermeable to large proteins, becomes compromised and allows proteins to pass into the filtrate. Therefore, proteinuria indicates glomerular damage, rather than dehydration-related mechanisms or protein secretion.
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