Why does sepsis cause widespread organ damage in the human body, despite antibiotics targeting the initial bacterial infection?

💡 Explanation

Sepsis leads to organ damage due to a cytokine storm, wherein the immune system's excessive release of cytokines causes systemic inflammation and tissue damage, because the immune response spirals out of control. Therefore, the organ damage stems from the immune response rather than the infection itself, rather than direct bacterial toxin effects.

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