Why does skin damage from ultraviolet exposure exacerbate acne more in individuals with overactive sebaceous glands, compared to those with normal sebum production?

💡 Explanation

UV exposure promotes lipid peroxidation in sebum, especially squalene. Because individuals with overactive sebaceous glands have higher squalene levels, this peroxidation triggers a greater inflammatory response, therefore leading to more severe acne, rather than simply increasing melanocyte activity or decreasing ceramide production.

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