A cancer cell with a mutated growth factor receptor divides rapidly despite DNA damage. Which outcome is most likely if the cell’s intrinsic apoptotic pathway is also disabled?

💡 Explanation

If both the growth factor receptor is mutated (driving proliferation) and the intrinsic apoptotic pathway is disabled, the cell loses its ability to undergo programmed cell death in response to DNA damage. This allows uncontrolled proliferation and tumor formation because the mutated cell can bypass normal checkpoints, therefore, the cell continues to divide, rather than undergoing apoptosis.

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