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← Human Body & HealthA patient with a genetic mutation has decreased Factor XIII production. If this patient sustains a deep wound, which coagulation outcome is most likely?
A)Rapid but weak clot formation
B)Unstable clot formation and lysis✓
C)Excessive thrombin and clotting
D)Normal clot, reduced inflammation
💡 Explanation
Decreased Factor XIII leads to unstable clot formation because Factor XIII is responsible for cross-linking fibrin monomers within the blood clot. Therefore, the clot forms initially, but fibrin cross-linking is impaired, leading to premature clot lysis, rather than stable clot formation.
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