Live Quiz Arena
🎁 1 Free Round Daily
⚡ Enter ArenaQuestion
← Human Body & HealthA patient with autoimmune disease experiences chronic inflammation. If a therapy targeting only TNF-alpha is applied, which consequence follows?
A)Complete resolution of immune dysregulation
B)Enhanced B-cell antibody production results
C)Increased susceptibility to viral infections
D)Compensatory upregulation of other cytokines✓
💡 Explanation
Blocking TNF-alpha can trigger compensatory mechanisms, because the immune system attempts to maintain homeostasis; therefore, other pro-inflammatory cytokines may increase to offset the reduction in TNF-alpha, rather than achieving complete resolution due to redundancy in cytokine signaling.
🏆 Up to £1,000 monthly prize pool
Ready for the live challenge? Join the next global round now.
*Terms apply. Skill-based competition.
Related Questions
Browse Human Body & Health →- During resistance training, why does eccentric contraction induce greater muscle hypertrophy compared to concentric contraction at the same load?
- If an elderly patient exhibits increased systemic oxidative stress, which consequence is most likely regarding bone health?
- If specialized pro-resolving mediators (SPMs) are deficient following lung injury, which consequence affecting the inflammatory cascade is most likely?
- If prolonged immobilization follows a femur fracture in a 70-year-old patient, which skeletal effect becomes most likely due to altered loading?
- Why does plasma osmolality sharply increase in a patient undergoing dialysis when the dialysate's sodium concentration is transiently set too high?
- Why does bacterial overgrowth cause malabsorption in the small intestine?
