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Human Body & Health

A patient with chronic kidney disease develops hyperkalemia. Which mechanism most directly explains why impaired renal function causes this electrolyte imbalance?

A)Increased aldosterone receptor sensitivity
B)Reduced potassium excretion in urine
C)Enhanced potassium reabsorption in nephron
D)Elevated distal tubule flow rate

💡 Explanation

Hyperkalemia arises in renal failure because the kidneys' ability to excrete potassium is reduced; therefore, potassium accumulates in the blood. This is due to impaired potassium secretion into the distal tubule and collecting duct, rather than increased reabsorption or altered aldosterone sensitivity.

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