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Human Body & Health

If a drug inhibits the urea cycle within liver hepatocytes, which consequence follows for the body's nitrogen balance?

A)Enhanced synthesis of glutamine occurs
B)Ketogenesis becomes the primary pathway
C)Glycogen stores are more rapidly depleted
D)Blood ammonia levels increase drastically

💡 Explanation

Inhibition of the urea cycle impairs the liver's ability to convert toxic ammonia into urea, because this cycle is essential for nitrogen detoxification. Therefore, blood ammonia levels rise, rather than glutamine synthesis increasing, as the liver fails to process nitrogenous waste.

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