If a patient with a known severe shellfish allergy accidentally consumes shrimp, which consequence is most likely?

💡 Explanation

Systemic vasodilation and hypotension result from anaphylaxis, because the ingestion of shellfish triggers IgE-mediated mast cell degranulation, releasing histamine and other mediators, therefore causing widespread vasodilation and a drop in blood pressure, rather than affecting gastric acid, blood cell count or liver function.

• If a drug with high hepatic clearance is administered orally but its bioavailability is much lower than expected, which mechanism explains this discrepancy?
• A researcher investigates the effects of aggregate formation on nerve cell function in Alzheimer's. Which mechanism explains why intracellular tau protein aggregates impair axonal transport in neurons?
• Why does significant muscle sarcopenia increase the risk of hip fractures, even when bone density, measured via DXA, remains relatively stable in an elderly patient?
• If a patient with chronic anemia receives a blood transfusion using blood stored for an extended period, which consequence follows regarding oxygen delivery?
• If a patient with a severe concussion experiences a prolonged metabolic crisis post-injury, which consequence involving glutamate excitotoxicity is most likely, given insufficient energy to maintain ion gradients?
• If a neuron's ubiquitin-proteasome system degrades less misfolded alpha-synuclein aggregate, which consequence follows?