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Life Sciences & Medicine

If cellular respiration lacks oxygen, which consequence follows in mammalian cells?

A)Increased ATP production via ETC
B)Krebs cycle activity increases tenfold
C)Fermentation regenerates NAD+ for glycolysis
D)Mitochondria synthesize more transmembrane proteins

💡 Explanation

Glycolysis requires NAD+ to proceed. Without oxygen, the electron transport chain shuts down, and fermentation becomes necessary to regenerate NAD+; because fermentation converts pyruvate to lactate (or ethanol), therefore NAD+ is available for glycolysis, rather than continuing aerobic respiration.

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