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← Human Body & HealthWhich outcome increases in an immune system undergoing chronic, granulomatous inflammation due to persistent undigested bacterial components like mycolic acids?
A)Formation of multinucleated giant cells✓
B)Increased acute phase protein production
C)Elevated levels of circulating lymphocytes
D)Enhanced antibody isotype switching
💡 Explanation
Chronic granulomatous inflammation results in persistent macrophage activation by indigestible substances, which causes recruitment and fusion of more macrophages via the mechanism of granuloma formation; therefore multinucleated giant cells form, rather than enhanced acute response or lymphocyte action which characterize acute inflammation.
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