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Human Body & Health

Which outcome increases in an immune system undergoing chronic, granulomatous inflammation due to persistent undigested bacterial components like mycolic acids?

A)Formation of multinucleated giant cells
B)Increased acute phase protein production
C)Elevated levels of circulating lymphocytes
D)Enhanced antibody isotype switching

💡 Explanation

Chronic granulomatous inflammation results in persistent macrophage activation by indigestible substances, which causes recruitment and fusion of more macrophages via the mechanism of granuloma formation; therefore multinucleated giant cells form, rather than enhanced acute response or lymphocyte action which characterize acute inflammation.

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