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← Human Body & HealthWhich outcome results when C5 convertase dysfunction occurs in a localized infection?
A)Reduced opsonization of pathogen surface✓
B)Decreased histamine release by mast
C)Increased cytotoxic T-cell proliferation
D)Systemic inflammatory response amplified
💡 Explanation
Reduced opsonization occurs because C5 convertase cleaves C5, triggering opsonization via C5b deposition. Without efficient C5 convertase activity deposition is reduced, therefore pathogens are less efficiently phagocytosed, rather than an inflammatory response getting amplified.
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