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← ScienceWhich risk escalates greatly at a DNA replication fork lacking primase?
A)Okazaki fragment formation decreases greatly
B)Unstable single-strand regions rapidly develop✓
C)Telomere shortening event decreases rapidly
D)Exonuclease proofreading activity begins failing
💡 Explanation
Unstable single-strand regions develop because DNA Polymerase requires a primer to initiate replication via phosphodiester bond formation rather than de novo synthesis. Replication stalling does eventually occur; therefore the answer is B, rather than decreased Okazaki fragments because these are consequences.
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