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Which risk escalates greatly at a DNA replication fork lacking primase?

A)Okazaki fragment formation decreases greatly
B)Unstable single-strand regions rapidly develop
C)Telomere shortening event decreases rapidly
D)Exonuclease proofreading activity begins failing

💡 Explanation

Unstable single-strand regions develop because DNA Polymerase requires a primer to initiate replication via phosphodiester bond formation rather than de novo synthesis. Replication stalling does eventually occur; therefore the answer is B, rather than decreased Okazaki fragments because these are consequences.

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