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Human Body & Health

Why does a Graafian follicle, dominant prior to ovulation, sometimes fail to release the oocyte even when LH surges?

A)Granulosa cells lack aromatase enzyme
B)Theca interna cells are non-responsive
C)Oocyte maturation inhibiting factor persists
D)Inadequate proteolytic enzyme production occurs

💡 Explanation

Ovulation requires proteolytic enzymes to weaken the follicle wall. Without adequate production, the oocyte can't be released, even with an LH surge, because the follicle doesn't rupture; therefore, the oocyte remains trapped within the follicle rather than being expelled into the fallopian tube.

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