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Human Body & Health

Why does a nerve impulse diminish beyond a synapse when neurotransmitter reuptake is highly effective?

A)Sodium channel refractory period prolongation
B)Reduced postsynaptic receptor binding
C)Increased action potential propagation speed
D)Elevated calcium influx at terminals

💡 Explanation

A highly effective neurotransmitter reuptake reduces the neurotransmitter concentration in the synaptic cleft; because of this, fewer neurotransmitters are available to bind to postsynaptic receptors, therefore, decreasing the likelihood of postsynaptic depolarization, rather than other processes that increase signal strength.

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