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Human Body & Health

Why does prolonged occlusion of skin via bandages promote opportunistic fungal infection?

A)Collagen breakdown stimulates fungal proteases
B)Reduced keratinocyte turnover impairs immunity
C)Sebum accumulation compromises skin barrier integrity
D)Elevated skin pH denatures antifungal peptides

💡 Explanation

Occlusion increases sebum accumulation, creating a moist, anaerobic environment that compromises the skin barrier, which opportunistic fungi exploit. Therefore, fungal infection risk rises, rather than collagen breakdown or pH change causing this, because the compromised barrier is the primary factor.

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