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Human Body & Health

A researcher observes that neutrophils exposed to interferon-gamma (IFN-γ) exhibit enhanced phagocytosis of Staphylococcus aureus. Why does this occur in the immune response?

A)Reduced MHC class I expression ensues
B)Lowered intracellular TNF-α production prevails
C)Decreased expression of Fcγ receptors happens
D)Increased antibody-dependent cell phagocytosis arises

💡 Explanation

IFN-γ enhances the immune system by promoting antibody-dependent cell phagocytosis. It upregulates Fcγ receptors on neutrophils, enabling increased binding to antibody-coated bacteria, because these receptors mediate the recognition and uptake of opsonized pathogens by phagocytes; therefore, phagocytosis increases, rather than decreasing due to other factors.

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