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← Human Body & HealthAs individuals age, the risk of sarcopenia increases, leading to reduced muscle mass and strength. Why does age-related decline in satellite cell function contribute significantly to this condition?
A)Decreased mTOR pathway activation predominates
B)Elevated myostatin expression promotes hypertrophy
C)Impaired muscle fiber regeneration occurs chronically✓
D)Increased proteasome activity preserves muscle
💡 Explanation
Sarcopenia progression relates to impaired regeneration because satellite cells are crucial for repairing damaged muscle fibers; age diminishes satellite cell functionality, therefore muscle tissue cannot be maintained effectively. This leads to loss, rather than preservation or enhanced growth, of muscle.
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