If a patient with impaired renal function takes a drug primarily cleared renally, what happens to the drug's half-life if the drug dosage is kept constant?

💡 Explanation

Reduced renal function decreases the drug's clearance from the body because the kidneys, which normally filter the drug, are not working efficiently. Therefore, the drug remains in the system longer, leading to an increased half-life, rather than being quickly eliminated.

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