Why does administering exogenous estrogen to a woman undergoing in vitro fertilization (IVF) often improve implantation rates?

💡 Explanation

Estrogen promotes endometrial receptivity by inducing changes in gene expression and cellular differentiation, thus creating an environment more conducive to blastocyst implantation. This occurs because estrogen upregulates key implantation factors; therefore, exogenous estrogen improves the chances of successful implantation, rather than directly affecting the blastocyst or immune cells.

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